From Medscape.com
Aaron I. Vinik, MD, PhD, FCP, FACP
At this year's EASD Meeting, the Camillo Golgi lecture was given by Professor Antonio Ceriello, Chair of Internal Medicine, University of Udine, Italy. Professor Ceriello has systematically studied the role of oxidative stress as a contributor to insulin resistance, as well as a possible factor affecting pancreatic islet dysfunction.[1] He proposed that free radicals were generated in excess, causing inflammation damaging to the endothelium of muscle, fat, and pancreatic islets. This concept thus implicates inflammation in both sides of the equation leading to the dysmetabolic syndrome and culminating in type 2 diabetes -- notably insulin resistance and impaired beta-cell function. Read more (free site, but requires registration)
